Levetiracetam

  • CAS No.: 102767-28-2
  • Molecular Formula: C8​H14​N2​O2​
  • Molecular Weight:170.21
  • Purity: ≥99.5%

Product Name: Levetiracetam

English alias: (S)-α-Ethyl-2-oxo-1-pyrrolidinylacetamide

    Product Introduction

    Levetiracetam (CAS: 102767-28-2) functions as a key chiral building block and chemical synthesis intermediate for advanced process development and laboratory research. It is highly suitable for evaluating downstream synthesis routes of pyrrolidone derivatives and preparing high-purity reference standards. In technical applications, this crystalline intermediate features outstanding chiral purity with a strictly controlled enantiomeric ratio, alongside excellent solubility in water and polar organic solvents. We ensure rigorous impurity control and reliable batch consistency across all manufacturing evaluations, backed by comprehensive COA and MSDS documentation for your purity review. To maintain chemical integrity, this material must be stored in tightly sealed containers in a cool, dry environment. Please verify local regulatory compliance before purchasing.

    CAS:102767-28-2

    Properties: White or off-white crystalline powder; odorless; slightly hygroscopic.

    Solubility: readily soluble in water, ethanol, and dichloromethane 、Almost insoluble in n-hexane and ether

    Melting point: 116–119°C

    Use: Antiepileptic active pharmaceutical ingredient

    Storage conditions: Store in a sealed container, protected from light, in a dry and cool place; temperature range: 10–25°C; Keep moisture-proof and sealed, away from oxidizers, strong acids, and strong bases.

    Product Characteristics

    • Unique Mechanism: It binds specifically to synaptic vesicle protein 2A (SV2A). This action modulates neurotransmitter release without targeting traditional ion channels or GABA receptors.
    • No Liver Enzyme Induction: It bypasses the hepatic cytochrome P450 enzyme system. This minimizes drug-drug interactions with other medications.
    • Excellent Pharmacokinetics: It offers rapid and complete absorption with nearly 100% oral bioavailability. It also features very low plasma protein binding (under 10%).
    • High Safety Profile: It causes minimal side effects. Physicians widely prescribe it to sensitive patient groups, including children, pregnant women, and the elderly.

    Product Uses

    • Partial-Onset Seizures: It serves as a monotherapy or adjunctive therapy for partial-onset seizures (with or without secondary generalization) in adults and children.
    • Myoclonic Seizures: It treats myoclonic seizures in patients with juvenile myoclonic epilepsy.
    • Generalized Tonic-Clonic Seizures: It helps control primary generalized tonic-clonic seizures in patients with idiopathic generalized epilepsy.

    Application Scenarios

    • First-Line Epilepsy Treatment: Neurologists and pediatricians frequently select it as a first-line drug for daily epilepsy management.
    • Emergency and ICU Care: Hospitals use its intravenous form to rapidly manage status epilepticus in emergency situations.
    • Diverse Formulation Development: Pharmaceutical companies purchase this Active Pharmaceutical Ingredient (API) to manufacture tablets, extended-release (XR) tablets, oral solutions, granules, and injections.

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