Product Introduction
Vonoprazan fumarate (CAS: 1260141-27-2) is a high-purity chemical synthesis intermediate intended strictly “for research-related use” and process development. It serves as an essential building block in laboratory-scale chemical synthesis and manufacturing evaluation. Our material offers exceptional batch consistency, with comprehensive COA and MSDS documentation available to ensure strict impurity control and precise purity review. Technologically, this crystalline powder exhibits excellent thermal and physical stability when kept under recommended storage conditions—stored in a cool, dry place and protected from light. This makes it highly reliable for analytical testing and process optimization. Buyers should confirm local regulatory requirements prior to procurement.
CAS:1260141-27-2
Properties: This product is a white to off-white crystalline powder; odorless.
Solubility: Soluble in dimethyl sulfoxide; slightly soluble in N,N-dimethylacetamide; slightly soluble in methanol and water; almost insoluble in isopropanol, acetone, and acetonitrile.
Usage: Potassium ion competitive acid blocker for the treatment of acid-related disorders, including gastric ulcers, duodenal ulcers, and reflux esophagitis.
Product Characteristics
- Fast Onset: It works from the very first dose. It does not need acid activation. It relieves heartburn on day one.
- Long-Lasting: It has a long half-life. It controls gastric acid for 24 hours. It effectively stops nighttime acid reflux.
- Food-Independent: Patients can take it with or without food. Meals do not affect its efficacy.
- Consistent Results: CYP2C19 enzymes do not drive its metabolism. It delivers the same stable effect across different patients.
- Acid-Stable: It remains highly stable in the acidic stomach environment. It directly binds to and blocks proton pumps.
Product Uses
- Acid-Related Diseases: It strongly suppresses stomach acid. It mainly treats erosive esophagitis (EE), gastric ulcers, and duodenal ulcers.
- H. pylori Eradication: It acts as the core acid blocker in eradication therapy. It quickly raises stomach pH above 6, helping antibiotics kill the bacteria effectively.
- NSAID Ulcer Prevention: It protects the stomach lining for patients taking daily aspirin or painkillers (NSAIDs) to prevent ulcers.
Application Scenarios
- First-line Clinical Use: Gastroenterologists prescribe it for severe acid reflux. It serves as the top choice when traditional PPIs fail.
- Combination Therapies for H. pylori: Drug companies combine it with antibiotics (like amoxicillin and clarithromycin) into co-packs to achieve high cure rates.
- API for Drug Manufacturing: Pharmaceutical companies purchase this Active Pharmaceutical Ingredient (API) to produce high-quality oral tablets.
